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In this episode of the HVMN Podcast, Drs. Her research focuses on studying non-toxic metabolic-targeted therapies for cancer.

His research focuses on ketones and the ketogenic diet.Īngela Poff, Ph.D is a Research Associate in the Department of Molecular Pharmacology and Physiology at the University of South Florida in Tampa, FL, and Co-Founder of Metabolic Health Initiative. He is also a Research Scientist at the Institute for Human and Machine Cognition (IHMC). ( is an Associate Professor in the Department of Molecular Pharmacology and Physiology at the University of South Florida Morsani College of Medicine. Instead, try a Mediterranean diet with exogenous ketones for supplementation with about 50-100g carbohydratesĭominic D’Agostino, Ph.D.A more diverse diet with plants, vegetables, different protein sources, with exogenous ketones would be more optimal.” – Dr. “Completely excluding carbohydrates, fruit, and vegetables to the extent we do that with a clinical ketogenic diet is not optimal.Tip: consuming carbohydrates with exogenous ketones (such as a ketone salt, MCT) will minimize glycemic variability.The greatest effect of ketogenic diet on athletic performance will likely be over time where you’ll see improvements in recovery, epigenetic effects, anti-inflammatory effects.Starting in early middle age, natural uptake of glucose declines but ketone uptake is retained in the aging brain – ketones can circumvent glucose transporter and provide the energy for proper function.Even within the ketogenic diet, there are many routes to go and options for exogenous ketones as supplement – like any diet, it needs to be personalized to your needs (a continuous glucose monitor can help).Ketones improve brain energy signaling metabolism, resilience, and enhance ability to maintain cognitive and physical performance in extreme environments – both environmental and physiologic.There should be a duty to disseminate translatable, clear research to the public if funded through government means.“Ketones can rapidly change brain energy metabolism and the neuropharmacology of your brain in a way that’s neuroprotective and anti-seizure.” – Dr.Explosion of ketones as a field of study: (1) ketones are a potent but accessible intervention (legal, accessed through diet or exogenous (2) scientists are living the lifestyle of what they’re studying which helps credibility, influence, experience.Where It Happens with Sahil Bloom and Greg IsenbergĬheck out the HVMN Podcast episode page Key Takeaways.This Week in Startups with Jason Calacanis.The Unraveling Podcast with Jocko Willink and Darryl Cooper.The Underworld Podcast with Danny Gold and Sean Williams.